Influence of Gag-Protease-Mediated Replication Capacity on Disease Progression in Individuals Recently Infected with HIV-1 Subtype C

HLA class I-mediated selection of immune escape mutations in functionally important Gag epitopes may partly explain slower disease progression in HIV-1-infected individuals with protective HLA alleles. To investigate the impact of Gag function on disease progression, the replication capacities of vi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wright, Jaclyn K., Novitsky, Vladimir, Brockman, Mark A., Brumme, Zabrina L., Brumme, Chanson J., Carlson, Jonathan M., Heckerman, David, Wang, Bingxia, Losina, Elena, Leshwedi, Mopo, van der Stok, Mary, Maphumulo, Lungile, Mkhwanazi, Nompumelelo, Chonco, Fundisiwe, Goulder, Philip J. R., Essex, Max, Walker, Bruce D., Ndung'u, Thumbi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126116/
https://ncbi.nlm.nih.gov/pubmed/21289112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02520-10
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge