Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters

The mechanisms underlying HIV-1 control by protective HLA class I alleles are not fully understood and could involve selection of escape mutations in functionally important Gag epitopes resulting in fitness costs. This study was undertaken to investigate, at the population level, the impact of HLA-m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wright, Jaclyn K., Brumme, Zabrina L., Carlson, Jonathan M., Heckerman, David, Kadie, Carl M., Brumme, Chanson J., Wang, Bingxia, Losina, Elena, Miura, Toshiyuki, Chonco, Fundisiwe, van der Stok, Mary, Mncube, Zenele, Bishop, Karen, Goulder, Philip J. R., Walker, Bruce D., Brockman, Mark A., Ndung'u, Thumbi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950592/
https://ncbi.nlm.nih.gov/pubmed/20702636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01084-10
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