Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters

The mechanisms underlying HIV-1 control by protective HLA class I alleles are not fully understood and could involve selection of escape mutations in functionally important Gag epitopes resulting in fitness costs. This study was undertaken to investigate, at the population level, the impact of HLA-m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wright, Jaclyn K., Brumme, Zabrina L., Carlson, Jonathan M., Heckerman, David, Kadie, Carl M., Brumme, Chanson J., Wang, Bingxia, Losina, Elena, Miura, Toshiyuki, Chonco, Fundisiwe, van der Stok, Mary, Mncube, Zenele, Bishop, Karen, Goulder, Philip J. R., Walker, Bruce D., Brockman, Mark A., Ndung'u, Thumbi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950592/
https://ncbi.nlm.nih.gov/pubmed/20702636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01084-10
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