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Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection
OBJECTIVE: We characterized protein-specific CD8+ T-cell immunodominance patterns during the first year of HIV-1 infection, and their impact on viral evolution and immune control. METHODS: We analyzed CD8+ T-cell responses to the full HIV-1 proteome during the first year of infection in eighteen ant...
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| Publicat a: | AIDS |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4427042/ https://ncbi.nlm.nih.gov/pubmed/25387316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000508 |
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