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Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

Sustained viremia following acute HIV infection is associated with profound CD4(+) T cell loss and exhaustion of HIV-specific CD8(+) T cell responses. To determine the impact of combination antiretroviral therapy (cART) on these processes, we examined the evolution of immune responses in acutely inf...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Ndhlovu, Zaza M., Kazer, Samuel W., Nkosi, Thandeka, Ogunshola, Funsho, Muema, Daniel M., Anmole, Gursev, Swann, Shayda A., Moodley, Amber, Dong, Krista, Reddy, Tarylee, Brockman, Mark A., Shalek, Alex K., Ndung’u, Thumbi, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901350/
https://ncbi.nlm.nih.gov/pubmed/31118290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau0528
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