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Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

Sustained viremia following acute HIV infection is associated with profound CD4(+) T cell loss and exhaustion of HIV-specific CD8(+) T cell responses. To determine the impact of combination antiretroviral therapy (cART) on these processes, we examined the evolution of immune responses in acutely inf...

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Dades bibliogràfiques
Publicat a:Sci Transl Med
Autors principals: Ndhlovu, Zaza M., Kazer, Samuel W., Nkosi, Thandeka, Ogunshola, Funsho, Muema, Daniel M., Anmole, Gursev, Swann, Shayda A., Moodley, Amber, Dong, Krista, Reddy, Tarylee, Brockman, Mark A., Shalek, Alex K., Ndung’u, Thumbi, Walker, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901350/
https://ncbi.nlm.nih.gov/pubmed/31118290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau0528
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