Functional Consequences of Human Immunodeficiency Virus Escape from an HLA-B*13-Restricted CD8(+) T-Cell Epitope in p1 Gag Protein

The observed association between HLA-B*13 and control of human immunodeficiency virus type 1 (HIV-1) infection has been linked to the number of Gag-specific HLA-B*13-restricted cytotoxic T-cell (CTL) responses identified. To date, the Gag escape mutations described that result in an in vitro fitness...

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Autores principales: Prado, Julia G., Honeyborne, Isobella, Brierley, Ian, Puertas, Maria Carmen, Martinez-Picado, Javier, Goulder, Philip J. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612351/
https://ncbi.nlm.nih.gov/pubmed/18945768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01882-08
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