Proliferative Capacity of Epitope-Specific CD8 T-Cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection

The relationship between the function of human immunodeficiency virus (HIV)-specific CD8 T-cell responses and viral load has not been defined. In this study, we used a panel of major histocompatibility complex class I tetramers to examine responses to frequently targeted CD8 T-cell epitopes in a lar...

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Main Authors: Day, Cheryl L., Kiepiela, Photini, Leslie, Alasdair J., van der Stok, Mary, Nair, Kriebashne, Ismail, Nasreen, Honeyborne, Isobella, Crawford, Hayley, Coovadia, Hoosen M., Goulder, Philip J. R., Walker, Bruce D., Klenerman, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2007
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797250/
https://ncbi.nlm.nih.gov/pubmed/17050606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01754-06
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