Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape

Recent studies have suggested greater HIV cure potential among infected children than adults. A major obstacle to HIV eradication in adults is that the viral reservoir is largely comprised of HIV-specific cytotoxic T lymphocyte (CTL) escape variants. We here evaluate the potential for CTL in HIV-inf...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Leitman, Ellen M., Thobakgale, Christina F., Adland, Emily, Ansari, M. Azim, Raghwani, Jayna, Prendergast, Andrew J., Tudor-Williams, Gareth, Kiepiela, Photini, Hemelaar, Joris, Brener, Jacqui, Tsai, Ming-Han, Mori, Masahiko, Riddell, Lynn, Luzzi, Graz, Jooste, Pieter, Ndung’u, Thumbi, Walker, Bruce D., Pybus, Oliver G., Kellam, Paul, Naranbhai, Vivek, Matthews, Philippa C., Gall, Astrid, Goulder, Philip J.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679167/
https://ncbi.nlm.nih.gov/pubmed/28983013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162123
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