Nef-Specific CD8+ T Cell Responses Contribute to HIV-1 Immune Control

Recent studies in the SIV-macaque model of HIV infection suggest that Nef-specific CD8+ T-cell responses may mediate highly effective immune control of viraemia. In HIV infection Nef recognition dominates in acute infection, but in large cohort studies of chronically infected subjects, breadth of T...

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Autors principals: Adland, Emily, Carlson, Jonathan M., Paioni, Paolo, Kløverpris, Henrik, Shapiro, Roger, Ogwu, Anthony, Riddell, Lynn, Luzzi, Graz, Chen, Fabian, Balachandran, Thambiah, Heckerman, David, Stryhn, Anette, Edwards, Anne, Ndung’u, Thumbi, Walker, Bruce D., Buus, Søren, Goulder, Philip, Matthews, Philippa C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759414/
https://ncbi.nlm.nih.gov/pubmed/24023819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073117
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