Structural Analogues of Smoothened Intracellular Loops as Potent Inhibitors of Hedgehog Pathway and Cancer Cell Growth

Por Remsberg, Jarrett R., Lou, Hong, Tarasov, Sergey G., Dean, Michael, Tarasova, Nadya I.
Publicado em 2007

A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells

Por Lu, Xiuxiu, Liu, Fen, Durham, Sarah E., Tarasov, Sergey G., Walters, Kylie J.
Publicado no PLoS One (2015)

Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 reveal distinct binding mechanisms between substrate receptors and shuttle factors of the proteasome

Por Chen, Xiang, Randles, Leah, Shi, Ke, Tarasov, Sergey G., Aihara, Hideki, Walters, Kylie J
Publicado no Structure (2016)

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis

Por Khavrutskii, Lyuba, Yeh, Joanna, Timofeeva, Olga, Tarasov, Sergey G., Pritt, Samuel, Stefanisko, Karen, Tarasova, Nadya
Publicado em 2013

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3′ end of 16S rRNA

Por Tu, Chao, Zhou, Xiaomei, Tarasov, Sergey G., Tropea, Joseph E., Austin, Brian P., Waugh, David S., Court, Donald L., Ji, Xinhua
Publicado em 2011

Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination

Por Stagno, Jason R., Altieri, Amanda S., Bubunenko, Mikhail, Tarasov, Sergey G., Li, Jess, Court, Donald L., Byrd, R. Andrew, Ji, Xinhua
Publicado em 2011

Peptide structure stabilization by membrane anchoring and its general applicability for the development of potent cell permeable inhibitors

Por Johannessen, Liv, Remsberg, Jarrett, Gaponenko, Vadim, Adams, Kristie M., Barchi, Joseph J., Tarasov, Sergey G., Jiang, Sheng, Tarasova, Nadya I.
Publicado em 2011

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

Por Pazgier, Marzena, Liu, Min, Zou, Guozhang, Yuan, Weirong, Li, Changqing, Li, Chong, Li, Jing, Monbo, Juahdi, Zella, Davide, Tarasov, Sergey G., Lu, Wuyuan
Publicado em 2009

Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

Por Li, Chong, Pazgier, Marzena, Li, Jing, Li, Changqing, Liu, Min, Zou, Guozhang, Li, Zhenyu, Chen, Jiandong, Tarasov, Sergey G., Lu, Wei-Yue, Lu, Wuyuan
Publicado em 2010

Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine

Por Das, Ranabir, Liang, Yu-He, Mariano, Jennifer, Li, Jess, Huang, Tao, King, Aaren, Tarasov, Sergey G, Weissman, Allan M, Ji, Xinhua, Byrd, R Andrew
Publicado em 2013

Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles

Por Tarasov, Sergey G., Gaponenko, Vadim, Howard, O. M. Zack, Chen, Yuhong, Oppenheim, Joost J., Dyba, Marzena A., Subramaniam, Sriram, Lee, Youngshim, Michejda, Christopher, Tarasova, Nadya I.
Publicado em 2011

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site

Por Chavan, Tanmay S., Jang, Hyunbum, Khavrutskii, Lyuba, Abraham, Sherwin J., Banerjee, Avik, Freed, Benjamin C., Johannessen, Liv, Tarasov, Sergey G., Gaponenko, Vadim, Nussinov, Ruth, Tarasova, Nadya I.
Publicado no Biophys J (2015)

BETA DEFENSIN 2 AND 3 PROMOTE THE UPTAKE OF SELF OR CpG DNA, ENHANCE IFN-α PRODUCTION BY HUMAN PLASMACYTOID DENDRITIC CELLS AND PROMOTE INFLAMMATION

Por Tewary, Poonam, dela Rosa, Gonzalo, Sharma, Neeraj, Rodriguez, Luis G, Tarasov, Sergey G, Howard, OM Zack, Shirota, Hidekazu, Steinhagen, Folkert, Klinman, Dennis M., Yang, De, Oppenheim, Joost J.
Publicado no J Immunol (2013)

Engineered Human Antibody Constant Domains with Increased Stability

Por Gong, Rui, Vu, Bang K., Feng, Yang, Prieto, DaRue A., Dyba, Marzena A., Walsh, Joseph D., Prabakaran, Ponraj, Veenstra, Timothy D., Tarasov, Sergey G., Ishima, Rieko, Dimitrov, Dimiter S.
Publicado em 2009

Allosteric Activation of E2-RING Finger Mediated Ubiquitylation by a Structurally-Defined Specific E2 Binding Region of gp78

Por Das, Ranabir, Mariano, Jennifer, Tsai, Yien Che, Kalathur, Ravi C., Kostova, Zlatka, Li, Jess, Tarasov, Sergey G., McFeeters, Robert L., Altieri, Amanda S., Ji, Xinhua, Byrd, R. Andrew, Weissman, Allan M.
Publicado em 2009

Mechanisms of Unphosphorylated STAT3 Transcription Factor Binding to DNA

Por Timofeeva, Olga A., Chasovskikh, Sergey, Lonskaya, Irina, Tarasova, Nadya I., Khavrutskii, Lyuba, Tarasov, Sergey G., Zhang, Xueping, Korostyshevskiy, Valeriy R., Cheema, Amrita, Zhang, Lihua, Dakshanamurthy, Sivanesan, Brown, Milton L., Dritschilo, Anatoly
Publicado em 2012

GTP-Dependent K-Ras Dimerization

Por Muratcioglu, Serena, Chavan, Tanmay S., Freed, Benjamin C., Jang, Hyunbum, Khavrutskii, Lyuba, Freed, R. Natasha, Dyba, Marzena A., Stefanisko, Karen, Tarasov, Sergey G., Gursoy, Attila, Keskin, Ozlem, Tarasova, Nadya I., Gaponenko, Vadim, Nussinov, Ruth
Publicado no Structure (2015)

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

Por Shi, Yuan, Chen, Xiang, Elsasser, Suzanne, Stocks, Bradley B., Tian, Geng, Lee, Byung-Hoon, Shi, Yanhong, Zhang, Naixia, de Poot, Stefanie A. H., Tuebing, Fabian, Sun, Shuangwu, Vannoy, Jacob, Tarasov, Sergey G., Engen, John R., Finley, Daniel, Walters, Kylie J.
Publicado no Science (2016)