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Peptide structure stabilization by membrane anchoring and its general applicability for the development of potent cell permeable inhibitors

Isolated protein motifs that are involved in interactions with their binding partners can be used to inhibit these interactions. However, peptides corresponding to protein fragments tend to have no defined secondary or tertiary structures in the absence of scaffolding by the rest of protein molecule...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Johannessen, Liv, Remsberg, Jarrett, Gaponenko, Vadim, Adams, Kristie M., Barchi, Joseph J., Tarasov, Sergey G., Jiang, Sheng, Tarasova, Nadya I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493468/
https://ncbi.nlm.nih.gov/pubmed/21365731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000563
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