Ubiquitin and Drug Discovery: Challenges and Opportunities

Por Weissman, Allan M.
Publicado em 2013

RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

Por Lipkowitz, Stanley, Weissman, Allan M.
Publicado em 2011

The Unfolded Protein Response, Degradation from the Endoplasmic Reticulum, and Cancer

Por Tsai, Yien Che, Weissman, Allan M.
Publicado em 2010

Ubiquitylation in ERAD: Reversing to Go Forward?

Por Tsai, Yien Che, Weissman, Allan M.
Publicado em 2011

Dissecting the Diverse Functions of the Metastasis Suppressor CD82/KAI1

Por Tsai, Yien Che, Weissman, Allan M.
Publicado em 2011

A Ubiquitin-Binding Rhomboid Protease Aimed at ERADication

Por Tsai, Yien Che, Weissman, Allan M.
Publicado em 2012

Compact Parkin only: insights into the structure of an autoinhibited ubiquitin ligase

Por Byrd, R Andrew, Weissman, Allan M
Publicado em 2013

Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein

Por Ishikura, Shuhei, Weissman, Allan M., Bonifacino, Juan S.
Publicado em 2010

The Predator becomes the Prey: Regulating the Ubiquitin System by Ubiquitylation and Degradation

Por Weissman, Allan M., Shabek, Nitzan, Ciechanover, Aaron
Publicado em 2011

Ubiquitin Ligases, Critical Mediators of Endoplasmic Reticulum-Associated Degradation

Por Kostova, Zlatka, Tsai, Yien Che, Weissman, Allan M.
Publicado em 2007

Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-de...

Por Yang, Mei, Omura, Satoshi, Bonifacino, Juan S., Weissman, Allan M.
Publicado em 1998

Cullin RING Ligases: Glommed by Glomulin

Por Hristova, Ventzislava A., Stringer, Daniel K., Weissman, Allan M.
Publicado em 2012

HECT and RING finger families of E3 ubiquitin ligases at a glance

Por Metzger, Meredith B., Hristova, Ventzislava A., Weissman, Allan M.
Publicado em 2012

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import

Por Plafker, Scott M., Plafker, Kendra S., Weissman, Allan M., Macara, Ian G.
Publicado em 2004

A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation

Por Kostova, Zlatka, Mariano, Jennifer, Scholz, Simone, Koenig, Carolin, Weissman, Allan M.
Publicado em 2009

Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7

Por Hann, Zachary S., Metzger, Meredith B., Weissman, Allan M., Lima, Christopher D.
Publicado no Acta Crystallogr F Struct Biol Commun (2019)

Targeting Tumor Cells Expressing p53 with a Water Soluble Inhibitor of Hdm2

Por Kitagaki, Jirouta, Agama, Keli K., Pommier, Yves, Yang, Yili, Weissman, Allan M.
Publicado em 2008

RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

Por Metzger, Meredith B., Pruneda, Jonathan N., Klevit, Rachel E., Weissman, Allan M.
Publicado em 2013

The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

Por Metzger, Meredith B., Scales, Jessica L., Dunklebarger, Mitchell F., Weissman, Allan M.
Publicado no G3 (Bethesda) (2017)

Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum

Por Shmueli, Ayelet, Tsai, Yien Che, Yang, Mei, Braun, Mary A., Weissman, Allan M.
Publicado em 2009