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Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 reveal distinct binding mechanisms between substrate receptors and shuttle factors of the proteasome

Three receptors (Rpn1/S2/PSMD2, Rpn10/S5a, Rpn13/Adrm1) in the proteasome bind substrates by interacting with conjugated ubiquitin chains and/or shuttle factors (Rad23/HR23, Dsk2/PLIC/ubiquilin, Ddi1) that carry ubiquitinated substrates to proteasomes. We solved the structure of two such receptors w...

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Bibliografski detalji
Izdano u:Structure
Glavni autori: Chen, Xiang, Randles, Leah, Shi, Ke, Tarasov, Sergey G., Aihara, Hideki, Walters, Kylie J
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972676/
https://ncbi.nlm.nih.gov/pubmed/27396824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.05.018
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