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The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression

Recently, we reported that bisbenzylidine piperidone RA190 adducts to Cys-88 of the proteasome ubiquitin receptor hRpn13, triggering accumulation of ubiquitinated proteins and endoplasmic reticulum stress-related apoptosis in various cancer cell lines. hRpn13 contains an N-terminal pleckstrin-like r...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Randles, Leah, Anchoori, Ravi K., Roden, Richard B. S., Walters, Kylie J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861445/
https://ncbi.nlm.nih.gov/pubmed/26907685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.694588
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