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Proteasome subunit Rpn13 is a novel ubiquitin receptor

Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation in eukaryotes. Here we report the identification of a new ubiquitin receptor, Rpn13/ARM1, a known component of the proteasome. Rpn13 binds ubiquitin via a conserved N-termi...

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Bibliografische gegevens
Hoofdauteurs: Husnjak, Koraljka, Elsasser, Suzanne, Zhang, Naixia, Chen, Xiang, Randles, Leah, Shi, Yuan, Hofmann, Kay, Walters, Kylie, Finley, Daniel, Dikic, Ivan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839886/
https://ncbi.nlm.nih.gov/pubmed/18497817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06926
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