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Structure of Proteasome Ubiquitin Receptor hRpn13 and its Activation by the Scaffolding Protein hRpn2
Rpn13 is a subunit of the proteasome that serves as a receptor for both ubiquitin and Uch37, one of the proteasome’s three deubiquitinating enzymes. We have determined the structure of full length human Rpn13 (hRpn13). Unexpectedly, the ubiquitin- and Uch37-binding domains of hRpn13 pack against eac...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887722/ https://ncbi.nlm.nih.gov/pubmed/20471946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.04.019 |
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