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Structure of hRpn10 bound to UBQLN2 UBL illustrates basis for complementarity between shuttle factors and substrates at the proteasome
The 26S proteasome is a highly complex 2.5 MDa molecular machine responsible for regulated protein degradation. Proteasome substrates are typically marked by ubiquitination for recognition at receptor sites contributed by Rpn1/S2/PSMD2, Rpn10/S5a, and Rpn13/Adrm1. Each receptor site can bind substra...
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| 出版年: | J Mol Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6389388/ https://ncbi.nlm.nih.gov/pubmed/30664872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.01.021 |
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