Expanding Trials of Novel Therapeutics for Rare Diseases Based on Grouping by Molecular Etiology

Por Brooks, P.J., Tagle, Danilo A., Groft, Steve
Publicado no Nat Biotechnol (2014)

Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases

Por Han, Qian, Cai, Tao, Tagle, Danilo A, Li, Jianyong
Publicado em 2010

Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

Por Han, Qian, Cai, Tao, Tagle, Danilo A., Li, Jianyong
Publicado em 2009

The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline

Por Sutherland, Margaret L, Fabre, Kristin M, Tagle, Danilo A
Publicado em 2013

Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships

Por Livingston, Christine A., Fabre, Kristin M., Tagle, Danilo A.
Publicado no Comput Struct Biotechnol J (2016)

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

Por HAN, Qian, CAI, Tao, TAGLE, Danilo A., ROBINSON, Howard, LI, Jianyong
Publicado em 2008

Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III

Por Han, Qian, Robinson, Howard, Cai, Tao, Tagle, Danilo A., Li, Jianyong
Publicado em 2009

Structural Insight into the Inhibition of Human Kynurenine Aminotransferase I/Glutamine transaminase K

Por Han, Qian, Robinson, Howard, Cai, Tao, Tagle, Danilo A., Li, Jianyong
Publicado em 2009

Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV

Por Han, Qian, Robinson, Howard, Cai, Tao, Tagle, Danilo A., Li, Jianyong
Publicado em 2011

The human proteome – a scientific opportunity for transforming diagnostics, therapeutics, and healthcare

Por Vidal, Marc, Chan, Daniel W, Gerstein, Mark, Mann, Matthias, Omenn, Gilbert S, Tagle, Danilo, Sechi, Salvatore
Publicado em 2012

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

Por Brown, Kevin D., Ziv, Yael, Sadanandan, Sunanda N., Chessa, Luciana, Collins, Francis S., Shiloh, Yosef, Tagle, Danilo A.
Publicado em 1997

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

Por Shirendeb, Ulziibat, Reddy, Arubala P., Manczak, Maria, Calkins, Marcus J., Mao, Peizhong, Tagle, Danilo A., Hemachandra Reddy, P.
Publicado em 2011

Biochemical and Phenotypic Abnormalities in Kynurenine Aminotransferase II-Deficient Mice

Por Yu, Ping, Di Prospero, Nicholas A., Sapko, Michael T., Cai, Tao, Chen, Amy, Melendez-Ferro, Miguel, Du, Fu, Whetsell, William O., Guidetti, Paolo, Schwarcz, Robert, Tagle, Danilo A.
Publicado em 2004

A recombination event that redefines the Huntington disease region

Por Snell, Russell G., Thompson, Leslie M., Tagle, Danilo A., Holloway, Tracey L., Barnes, Glenn, Harley, Helen G., Sandkuijl, Lodewijk A., MacDonald, Marcy E., Collins, Francis S., Gusella, James F., Harper, Peter S., Shaw, Duncan J.
Publicado em 1992

An Overview of the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Project

Por Meurer, William J., Lewis, Roger J., Tagle, Danilo, Fetters, Michael D, Legocki, Laurie, Berry, Scott, Connor, Jason, Durkalski, Valerie, Elm, Jordan, Zhao, Wenle, Frederiksen, Shirley, Silbergleit, Robert, Palesch, Yuko, Berry, Donald A., Barsan, William G.
Publicado em 2012

Substantial narrowing of the Niemann–Pick C candidate interval by yeast artificial chromosome complementation

Por Gu, Jessie Z., Carstea, Eugene D., Cummings, Christiano, Morris, Jill A., Loftus, Stacie K., Zhang, Dana, Coleman, Katherine G., Cooney, Adele M., Comly, Marcy E., Fandino, Laura, Roff, Calvin, Tagle, Danilo A., Pavan, William J., Pentchev, Peter G., Rosenfeld, Melissa A.
Publicado em 1997

The NIH Extracellular RNA Communication Consortium

Por Ainsztein, Alexandra M., Brooks, Philip J., Dugan, Vivien G., Ganguly, Aniruddha, Guo, Max, Howcroft, T. Kevin, Kelley, Christine A., Kuo, Lillian S., Labosky, Patricia A., Lenzi, Rebecca, McKie, George A., Mohla, Suresh, Procaccini, Dena, Reilly, Matthew, Satterlee, John S., Srinivas, Pothur R., Church, Elizabeth Stansell, Sutherland, Margaret, Tagle, Danilo A., Tucker, Jessica M., Venkatachalam, Sundar
Publicado no J Extracell Vesicles (2015)

Stem cell-derived models to improve mechanistic understanding and prediction of human drug induced liver injury

Por Goldring, Christopher, Antoine, Daniel J., Bonner, Frank, Crozier, Jonathan, Denning, Chris, Fontana, Robert J., Hanley, Neil A., Hay, David C., Ingelman-Sundberg, Magnus, Juhila, Satu, Kitteringham, Neil, Silva-Lima, Beatriz, Norris, Alan, Pridgeon, Chris, Ross, James A., Sison Young, Rowena, Tagle, Danilo, Tornesi, Belen, van de Water, Bob, Weaver, Richard J., Zhang, Fang, Park, B. Kevin
Publicado no Hepatology (2016)

Perspectives on Best Practices for Gene Therapy Programs

Por Cheever, Thomas R., Berkley, Dale, Braun, Serge, Brown, Robert H., Byrne, Barry J., Chamberlain, Jeffrey S., Cwik, Valerie, Duan, Dongsheng, Federoff, Howard J., High, Katherine A., Kaspar, Brian K., Klinger, Katherine W., Larkindale, Jane, Lincecum, John, Mavilio, Fulvio, McDonald, Cheryl L., McLaughlin, James, Weiss McLeod, Bonnie, Mendell, Jerry R., Nuckolls, Glen, Stedman, Hansell H., Tagle, Danilo A., Vandenberghe, Luk H., Wang, Hao, Wernett, Pamela J., Wilson, James M., Porter, John D., Gubitz, Amelie K.
Publicado no Hum Gene Ther (2015)

Biology-inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing

Por Marx, Uwe, Andersson, Tommy B., Bahinski, Anthony, Beilmann, Mario, Beken, Sonja, Cassee, Flemming R., Cirit, Murat, Daneshian, Mardas, Fitzpatrick, Susan, Frey, Olivier, Gaertner, Claudia, Giese, Christoph, Griffith, Linda, Hartung, Thomas, Heringa, Minne B., Hoeng, Julia, de Jong, Wim H., Kojima, Hajime, Kuehnl, Jochen, Luch, Andreas, Maschmeyer, Ilka, Sakharov, Dmitry, Sips, Adrienne J. A. M., Steger-Hartmann, Thomas, Tagle, Danilo A., Tonevitsky, Alexander, Tralau, Tewes, Tsyb, Sergej, van de Stolpe, Anja, Vandebriel, Rob, Vulto, Paul, Wang, Jufeng, Wiest, Joachim, Rodenburg, Marleen, Roth, Adrian
Publicado no ALTEX (2016)