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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

Kynurenine aminotransferases (KATs) catalyze the synthesis of kynurenic acid (KYNA), an endogenous antagonist of N-methyl-d-aspartate and alpha 7-nicotinic acetylcholine receptors. Abnormal KYNA levels in human brains are implicated in the pathophysiology of schizophrenia, Alzheimer's disease,...

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Detalhes bibliográficos
Main Authors: Han, Qian, Cai, Tao, Tagle, Danilo A., Li, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867614/
https://ncbi.nlm.nih.gov/pubmed/19826765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-009-0166-4
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