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Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II
KAT (kynurenine aminotransferase) II is a primary enzyme in the brain for catalysing the transamination of kynurenine to KYNA (kynurenic acid). KYNA is the only known endogenous antagonist of the N-methyl-d-aspartate receptor. The enzyme also catalyses the transamination of aminoadipate to α-oxoadip...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2559858/ https://ncbi.nlm.nih.gov/pubmed/18620547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20080085 |
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