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Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases

BACKGROUND: Kynurenine aminotransferase (KAT) catalyzes the transamination of kynunrenine to kynurenic acid (KYNA). KYNA is a neuroactive compound and functions as an antagonist of alpha7-nicotinic acetylcholine receptors and is the only known endogenous antagonist of N-methyl-D-aspartate receptors....

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Detalhes bibliográficos
Main Authors: Han, Qian, Cai, Tao, Tagle, Danilo A, Li, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890522/
https://ncbi.nlm.nih.gov/pubmed/20482848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-19
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