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Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases
BACKGROUND: Kynurenine aminotransferase (KAT) catalyzes the transamination of kynunrenine to kynurenic acid (KYNA). KYNA is a neuroactive compound and functions as an antagonist of alpha7-nicotinic acetylcholine receptors and is the only known endogenous antagonist of N-methyl-D-aspartate receptors....
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890522/ https://ncbi.nlm.nih.gov/pubmed/20482848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-19 |
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