MAP Kinase Activated Protein Kinase-2 in Cardiac Hypertrophy and Cyclooxygenase-2 Regulation in Heart: Streicher: MK2 in Cardiac Hypertrophy and COX-2 Regulation

Por Streicher, John M., Ren, Shuxun, Herschman, Harvey, Wang, Yibin
Publicado em 2010

Compensatory Hypertrophy Induced by Ventricular Cardiomyocyte Specific COX-2 Expression in Mice

Por Streicher, John M., Kamei, Kenichiro, Ishikawa, Tomo-o, Herschman, Harvey, Wang, Yibin
Publicado em 2010

Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt

Por Schmid, Cullen L, Streicher, John M, Meltzer, Herbert Y, Bohn, Laura M
Publicado em 2014

Behavioral and Cellular Pharmacology Characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3′-carboxamido)morphinan (NAQ) as a Mu Opioid Receptor Sel...

Por Zhang, Yan, Braithwaite, Amanda, Yuan, Yunyun, Streicher, John M., Bilsky, Edward J.
Publicado em 2014

Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain

Por Olson, Keith M., Lei, Wei, Keresztes, Attila, LaVigne, Justin, Streicher, John M.
Publicado no Yale J Biol Med (2017)

Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2

Por Papanicolaou, Kyriakos N., Streicher, John M., Ishikawa, Tomo-o, Herschman, Harvey, Wang, Yibin, Walsh, Kenneth
Publicado em 2010

Functional Selectivity of 6′-Guanidinonaltrindole (6′-GNTI) at κ-Opioid Receptors in Striatal Neurons

Por Schmid, Cullen L., Streicher, John M., Groer, Chad E., Munro, Thomas A., Zhou, Lei, Bohn, Laura M.
Publicado em 2013

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

Por Béguin, Cécile, Potuzak, Justin, Xu, Wei, Liu-Chen, Lee-Yuan, Streicher, John M., Groer, Chad E., Bohn, Laura M., Carlezon, William A., Cohen, Bruce M.
Publicado em 2011

17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4′-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion

Por Zhang, Yan, Williams, Dwight A., Zaidi, Saheem A., Yuan, Yunyun, Braithwaite, Amanda, Bilsky, Edward J., Dewey, William L., Akbarali, Hamid I., Streicher, John M., Selley, Dana E.
Publicado no ACS Chem Neurosci (2016)

The mixed-action delta/mu opioid agonst MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of t...

Por Stevenson, Glenn W., Luginbuhl, Amy, Dunbar, Catherine, LaVigne, Justin, Dutra, Julio, Atherton, Phillip, Bell, Brooke, Cone, Katherine, Giuvelis, Denise, Polt, Robin, Streicher, John M., Bilsky, Edward J.
Publicado no Pharmacol Biochem Behav (2015)

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif

Por Frankowski, Kevin J., Slauson, Stephen R., Lovell, Kimberly M., Phillips, Angela M., Streicher, John M., Zhou, Lei, Whipple, David A., Schoenen, Frank J., Prisinzano, Thomas E., Bohn, Laura M., Aubé, Jeffrey
Publicado no Bioorg Med Chem (2014)

Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

Por Zhou, Lei, Lovell, Kimberly M., Frankowski, Kevin J., Slauson, Stephen R., Phillips, Angela M., Streicher, John M., Stahl, Edward, Schmid, Cullen L., Hodder, Peter, Madoux, Franck, Cameron, Michael D., Prisinzano, Thomas E., Aubé, Jeffrey, Bohn, Laura M.
Publicado em 2013

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy

Por Frankowski, Kevin J., Hedrick, Michael P., Gosalia, Palak, Li, Kelin, Shi, Shenghua, Whipple, David, Ghosh, Partha, Prisinzano, Thomas E., Schoenen, Frank J., Su, Ying, Vasile, S., Sergienko, Eduard, Gray, Wilson, Hariharan, Santosh, Milan, Loribelle, Heynen-Genel, Susanne, Mangravita-Novo, Arianna, Vicchiarelli, Michael, Smith, Layton H., Streicher, John M., Caron, Marc G., Barak, Lawrence S., Bohn, Laura M., Chung, Thomas D. Y., Aubé, Jeffrey
Publicado em 2012