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Behavioral and Cellular Pharmacology Characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3′-carboxamido)morphinan (NAQ) as a Mu Opioid Receptor Selective Ligand

Mu opioid receptor (MOR) selective antagonists and partial agonists have been used for the treatment of opioid abuse and addiction. Our recent efforts on the identification of MOR antagonists have provided several novel leads displaying interesting pharmacological profiles. Among them, 17-cyclopropy...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, Yan, Braithwaite, Amanda, Yuan, Yunyun, Streicher, John M., Bilsky, Edward J.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073486/
https://ncbi.nlm.nih.gov/pubmed/24815322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.04.041
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