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Behavioral and Cellular Pharmacology Characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3′-carboxamido)morphinan (NAQ) as a Mu Opioid Receptor Selective Ligand

Mu opioid receptor (MOR) selective antagonists and partial agonists have been used for the treatment of opioid abuse and addiction. Our recent efforts on the identification of MOR antagonists have provided several novel leads displaying interesting pharmacological profiles. Among them, 17-cyclopropy...

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Autori principali: Zhang, Yan, Braithwaite, Amanda, Yuan, Yunyun, Streicher, John M., Bilsky, Edward J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073486/
https://ncbi.nlm.nih.gov/pubmed/24815322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.04.041
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