Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens

por Amarachintha, Surya, Harmel-Laws, Eleana, Steinbrecher, Kris A.
Publicado en Sci Rep (2018)

Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent Transcription

por Steinbrecher, Kris A., Wilson, Willie, Cogswell, Patricia C., Baldwin, Albert S.
Publicado 2005

Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen

por Mann, Elizabeth A, Harmel-Laws, Eleana, Cohen, Mitchell B, Steinbrecher, Kris A
Publicado 2013

Inflammation-mediated Notch signaling skews Fanconi Anemia hematopoietic stem cell differentiation

por Du, Wei, Amarachintha, Surya, Sipple, Jared, Schick, Jonathan, Steinbrecher, Kris, Pang, Qishen
Publicado 2013

Guanylate Cyclase C Deficiency Causes Severe Inflammation in a Murine Model of Spontaneous Colitis

por Harmel-Laws, Eleana, Mann, Elizabeth A., Cohen, Mitchell B., Steinbrecher, Kris A.
Publicado 2013

Targeted Inactivation of the Mouse Guanylin Gene Results in Altered Dynamics of Colonic Epithelial Proliferation

por Steinbrecher, Kris A., Wowk, Steve A., Rudolph, Jeffrey A., Witte, David P., Cohen, Mitchell B.
Publicado 2002

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation

por Gilbert, Shila, Zhang, Rongli, Denson, Lee, Moriggl, Richard, Steinbrecher, Kris, Shroyer, Noah, Lin, James, Han, Xiaonan
Publicado 2012

Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11

por Waddell, Amanda, Ahrens, Richard, Steinbrecher, Kris, Donovan, Burke, Rothenberg, Marc E., Munitz, Ariel, Hogan, Simon P.
Publicado 2011

Loss of Guanylyl Cyclase C (GCC) Signaling Leads to Dysfunctional Intestinal Barrier

por Han, Xiaonan, Mann, Elizabeth, Gilbert, Shila, Guan, Yanfang, Steinbrecher, Kris A., Montrose, Marshall H., Cohen, Mitchell B.
Publicado 2011

Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice

por Waddell, Amanda, Ahrens, Richard, Tsai, Yi Ting, Sherrill, Joseph D., Denson, Lee A., Steinbrecher, Kris A., Hogan, Simon P.
Publicado 2013

Activation of TGF‐β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease

por Liu, Zhiwei, Kong, Fansheng, Vallance, Jefferson E., Harmel‐Laws, Eleana, Amarachintha, Surya, Steinbrecher, Kris A., Rosen, Michael J., Bhattacharyya, Sandip
Publicado en Physiol Rep (2017)

Commensal microbes drive intestinal inflammation by IL-17–producing CD4(+) T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2

por Xin, Lijun, Jiang, Tony T., Chaturvedi, Vandana, Kinder, Jeremy M., Ertelt, James M., Rowe, Jared H., Steinbrecher, Kris A., Way, Sing Sing
Publicado 2014

Myeloid-derived NF-κB negative regulation of PU.1 and cEBPβ-driven pro-inflammatory cytokine production restrains LPS-induced Shock

por Vanoni, Simone, Tsai, Yi Ting, Waddell, Amanda, Waggoner, Lisa, Klarquist, Jared, Divanovic, Senad, Hoebe, Kasper, Steinbrecher, Kris A., Hogan, Simon P.
Publicado en Innate Immun (2016)

Murine Guanylate Cyclase C Regulates Colonic Injury and Inflammation

por Steinbrecher, Kris A., Harmel-Laws, Eleana, Garin-Laflam, Monica P., Mann, Elizabeth A., Bezerra, Lucas D., Hogan, Simon P., Cohen, Mitchell B.
Publicado 2011

NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8(+) T cells for tumor promotion

por Li, Liwen, Han, Lei, Sun, Fan, Zhou, Jingjiao, Ohaegbulam, Kim C., Tang, Xudong, Zang, Xingxing, Steinbrecher, Kris A., Qu, Zhaoxia, Xiao, Gutian
Publicado en Oncoimmunology (2018)

Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

por Ikpa, Pauline T., Sleddens, Hein F. B. M., Steinbrecher, Kris A., Peppelenbosch, Maikel P., de Jonge, Hugo R., Smits, Ron, Bijvelds, Marcel J. C.
Publicado en Histochem Cell Biol (2016)

Paired immunoglobulin-like Receptor B (PIR-B) Negatively Regulates Macrophage Activation in Experimental Colitis

por Munitz, Ariel, Cole, Eric T., Waddell, Amanda, Groschwitz, Katherine, Ahrens, Richard, Steinbrecher, Kris, Willson, Tara, Han, Xiaonan, Denson, Lee, Rothenberg, Marc E., Hogan, Simon P
Publicado 2010

Deletion of Fanca or Fancd2 dysregulates Treg in mice

por Du, Wei, Erden, Ozlem, Wilson, Andrew, Sipple, Jared M., Schick, Jonathan, Mehta, Parinda, Myers, Kasiani C., Steinbrecher, Kris A., Davies, Stella M., Pang, Qishen
Publicado 2014

Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis

por Begg, Denovan P., Steinbrecher, Kris A., Mul, Joram D., Chambers, Adam P., Kohli, Rohit, Haller, April, Cohen, Mitchell B., Woods, Stephen C., Seeley, Randy J.
Publicado 2014

Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses

por Zhang, Rongli, Gilbert, Shila, Yao, Xinsheng, Vallance, Jefferson, Steinbrecher, Kris, Moriggl, Richard, Zhang, Dongsheng, Eluri, Madhu, Chen, Haifeng, Cao, Huiqing, Shroyer, Noah, Denson, Lee, Han, Xiaonan
Publicado en Pharmacol Res Perspect (2015)