Apomorphine and Alzheimer's Aβ: Roles for Regulated α Cleavage, Autophagy, Antioxidation?

Tekijä Steele, John W., Gandy, Sam
Julkaistu 2011

Latrepirdine (Dimebon(®)), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model

Tekijä Steele, John W., Gandy, Sam
Julkaistu 2013

Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells

Tekijä Ordonez, M. Paulina, Steele, John W.
Julkaisussa Brain Res (2016)

One carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects?

Tekijä Steele, John W, Kim, Sung-Eun, Finnell, Richard H
Julkaisussa Biochimie (2020)

Modulation of Autophagy as a Therapeutic Target for Alzheimer’s Disease

Tekijä Steele, John W., Fan, Emily, Kelahmetoglu, Yildiz, Tian, Yuan, Bustos, Victor
Julkaisussa Postdoc J (2013)

Bringing dead proteins back to life

Tekijä A Wustman, Brandon, Steele, John W, Sjoberg, Eric R, Stevens, Anthony C
Julkaistu 2014

Protein Sorting Motifs in the Cytoplasmic Tail of SorCS1 Control Generation of Alzheimer's Amyloid-β Peptide

Tekijä Lane, Rachel F., Steele, John W., Cai, Dongming, Ehrlich, Michelle E., Attie, Alan D., Gandy, Sam
Julkaistu 2013

Light-dependent N-end rule-mediated disruption of protein function in Saccharomyces cerevisiae and Drosophila melanogaster

Tekijä Stevens, Leslie M., Kim, Goheun, Koromila, Theodora, Steele, John W., McGehee, James, Stathopoulos, Angelike, Stein, David S.
Julkaisussa PLoS Genet (2021)

The Antagonism of Folate Receptor by Dolutegravir: Developmental Toxicity Reduction by Supplemental Folic Acid

Tekijä CABRERA, Robert M., SOUDER, Jaclyn P., STEELE, John W., YEO, Lythou, TUKEMAN, Gabriel, GORELICK, Daniel A., FINNELL, Richard H.
Julkaisussa AIDS (2019)

MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure

Tekijä Keuls, Rachel A., Kojima, Karin, Lozzi, Brittney, Steele, John W., Chen, Qiuying, Gross, Steven S., Finnell, Richard H., Parchem, Ronald J.
Julkaisussa Int J Mol Sci (2020)

The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer's disease

Tekijä Brautigam, Hannah, Steele, John W, Westaway, David, Fraser, Paul E, George-Hyslop, Peter H St, Gandy, Sam, Hof, Patrick R, Dickstein, Dara L
Julkaistu 2012

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-β Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

Tekijä Lane, Rachel F., Raines, Summer M., Steele, John W., Ehrlich, Michelle E., Lah, James A., Small, Scott A., Tanzi, Rudolph E., Attie, Alan D., Gandy, Sam
Julkaistu 2010

Molecular Topology as Novel Strategy for Discovery of Drugs with Aβ Lowering and Anti-Aggregation Dual Activities for Alzheimer’s Disease

Tekijä Wang, Jun, Land, David, Ono, Kenjiro, Galvez, Jorge, Zhao, Wei, Vempati, Prashant, Steele, John W., Cheng, Alice, Yamada, Masahito, Levine, Samara, Mazzola, Paolo, Pasinetti, Giulio M.
Julkaistu 2014

Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele

Tekijä Steele, John W., Bayliss, Sharon, Bayliss, John, Lin, Ying Linda, Wlodarczyk, Bogdan J., Cabrera, Robert M., Asfaw, Yohannes G., Cummings, Thomas J., Finnell, Richard H., George, Timothy M.
Julkaisussa J Pediatr Surg (2019)

Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1−/− phenotype and forms complexes with wildtype PS1 and nicastrin

Tekijä Brautigam, Hannah, Moreno, Cesar L., Steele, John W., Bogush, Alexey, Dickstein, Dara L., Kwok, John B.J., Schofield, Peter R., Thinakaran, Gopal, Mathews, Paul M., Hof, Patrick R., Gandy, Sam, Ehrlich, Michelle E.
Julkaisussa Sci Rep (2015)

CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression

Tekijä Cao, Xuanye, Wolf, Annika, Kim, Sung-Eun, Cabrera, Robert M., Wlodarczyk, Bogdan J., Zhu, Huiping, Parker, Margaret, Lin, Ying, Steele, John W., Han, Xiao, Ramaekers, Vincent Th, Steinfeld, Robert, Finnell, Richard H., Lei, Yunping
Julkaisussa J Med Genet (2021)

Acute dosing of latrepirdine (Dimebon™), a possible Alzheimer therapeutic, elevates extracellular amyloid-β levels in vitro and in vivo

Tekijä Steele, John W, Kim, Soong H, Cirrito, John R, Verges, Deborah K, Restivo, Jessica L, Westaway, David, Fraser, Paul, Hyslop, Peter St George, Sano, Mary, Bezprozvanny, Ilya, Ehrlich, Michelle E, Holtzman, David M, Gandy, Sam
Julkaistu 2009

Early Fear Memory Defects Are Associated with Altered Synaptic Plasticity and Molecular Architecture in the TgCRND8 Alzheimer's Disease Mouse Model

Tekijä Steele, John W., Brautigam, Hannah, Short, Jennifer A., Sowa, Allison, Shi, Mengxi, Yadav, Aniruddha, Weaver, Christina M., Westaway, David, Fraser, Paul E., St George-Hyslop, Peter H., Gandy, Sam, Hof, Patrick R., Dickstein, Dara L.
Julkaisussa J Comp Neurol (2014)

Days-to-criterion as an indicator of toxicity associated with human Alzheimer amyloid-β oligomers

Tekijä Gandy, Sam, Simon, Adam J., Steele, John W., Lublin, Alex L., Lah, James J., Walker, Lary C., Levey, Allan I., Krafft, Grant A., Levy, Efrat, Checler, Frédéric, Glabe, Charles, Bilker, Warren, Abel, Ted, Schmeidler, James, Ehrlich, Michelle E.
Julkaistu 2010

Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes

Tekijä Knight, Elysse M., Kim, Soong Ho, Kottwitz, Jessica C., Hatami, Asa, Albay, Ricardo, Suzuki, Akinobu, Lublin, Alex, Alberini, Cristina M., Klein, William L., Szabo, Paul, Relkin, Norman R., Ehrlich, Michelle, Glabe, Charles G., Gandy, Sam, Steele, John W.
Julkaisussa Neurol Neuroimmunol Neuroinflamm (2016)