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Days-to-criterion as an indicator of toxicity associated with human Alzheimer amyloid-β oligomers
OBJECTIVES: Recent evidence suggests that high molecular weight soluble oligomeric Aβ (oAβ) assemblies (also known as Aβ-derived diffusible ligands, or ADDLs) may represent a primary neurotoxic basis for cognitive failure in AD. To date, in vivo studies of oAβ/ADDLs have involved injection of assemb...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094694/ https://ncbi.nlm.nih.gov/pubmed/20641005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22052 |
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