लोड हो रहा है...

Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein

Recent data suggest that intraneuronal accumulation of metabolites of the amyloid β precursor protein (APP) is neurotoxic. We observed that transgenic mice overexpressing in neurons a human APP gene harboring the APP(E693Q) (Dutch) mutation have intraneuronal lysosomal accumulation of APP carboxyl-t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Psychiatry
मुख्य लेखकों: Kaur, Gurjinder, Pawlik, Monika, Gandy, Sam E., Ehrlich, Michelle E., Smiley, John F., Levy, Efrat
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405008/
https://ncbi.nlm.nih.gov/pubmed/27777419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.189
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!