A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients

Down syndrome (DS) is characterized by cognitive deficits throughout the lifespan and with the development of aging-dependent Alzheimer’s type neuropathology, which is related to the triplication of the amyloid β precursor protein (APP) gene. A dysfunctional endosomal system in neurons is an early c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Pérez-González, Rocío, Gauthier, Sébastien A., Sharma, Ajay, Miller, Chelsea, Pawlik, Monika, Kaur, Gurjinder, Kim, Yohan, Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960325/
https://ncbi.nlm.nih.gov/pubmed/31479861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.07.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados