Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

A dysfunctional endosomal pathway and abnormally enlarged early endosomes in neurons are an early characteristic of Down syndrome (DS) and Alzheimer’s disease (AD). We have hypothesized that endosomal material can be released by endosomal multivesicular bodies (MVBs) into the extracellular space via...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Gauthier, Sébastien A., Pérez-González, Rocío, Sharma, Ajay, Huang, Fang-Ke, Alldred, Melissa J., Pawlik, Monika, Kaur, Gurjinder, Ginsberg, Stephen D., Neubert, Thomas A., Levy, Efrat
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576289/
https://ncbi.nlm.nih.gov/pubmed/28851452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0466-0
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker