Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

A dysfunctional endosomal pathway and abnormally enlarged early endosomes in neurons are an early characteristic of Down syndrome (DS) and Alzheimer’s disease (AD). We have hypothesized that endosomal material can be released by endosomal multivesicular bodies (MVBs) into the extracellular space via...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Gauthier, Sébastien A., Pérez-González, Rocío, Sharma, Ajay, Huang, Fang-Ke, Alldred, Melissa J., Pawlik, Monika, Kaur, Gurjinder, Ginsberg, Stephen D., Neubert, Thomas A., Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576289/
https://ncbi.nlm.nih.gov/pubmed/28851452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0466-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados