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Glutamatergic Transmission Aberration: A Major Cause of Behavioral Deficits in a Murine Model of Down's Syndrome

Trisomy 21, or Down's syndrome (DS), is the most common genetic cause of intellectual disability. Altered neurotransmission in the brains of DS patients leads to hippocampus-dependent learning and memory deficiency. Although genetic mouse models have provided important insights into the genes a...

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Detalhes bibliográficos
Main Authors: Kaur, Gurjinder, Sharma, Ajay, Xu, Wenjin, Gerum, Scott, Alldred, Melissa J., Subbanna, Shivakumar, Basavarajappa, Balapal S., Pawlik, Monika, Ohno, Masuo, Ginsberg, Stephen D., Wilson, Donald A., Guilfoyle, David N., Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983795/
https://ncbi.nlm.nih.gov/pubmed/24719089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5338-13.2014
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