Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

BACKGROUND: The multifunctional protein vitronectin is present within the deposits associated with Alzheimer disease (AD), age-related macular degeneration (AMD), atherosclerosis, systemic amyloidoses, and glomerulonephritis. The extent to which vitronectin contributes to amyloid formation within th...

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Main Authors: Shin, Thuzar M, Isas, J Mario, Hsieh, Chia-Ling, Kayed, Rakez, Glabe, Charles G, Langen, Ralf, Chen, Jeannie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577670/
https://ncbi.nlm.nih.gov/pubmed/18939994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-3-16
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