Soluble and Mature Amyloid Fibrils in Drusen Deposits

PURPOSE. Drusen are a hallmark of eyes affected by age-related macular degeneration. In previous study, a conformational-specific antibody showed drusen to contain nonfibrillar amyloid structures. The current study was undertaken to assess the presence of additional amyloid structures in drusen. MET...

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Main Authors: Isas, J. Mario, Luibl, Volker, Johnson, Lincoln V., Kayed, Rakez, Wetzel, Ronald, Glabe, Charles G., Langen, Ralf, Chen, Jeannie
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840723/
https://ncbi.nlm.nih.gov/pubmed/19892876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4207
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