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One carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects?

Neural tube defects (NTDs) are a broad class of congenital birth defects that result from the failure of neural tube closure during neurulation. Folic acid supplementation has been shown to prevent the occurrence of NTDs by as much as 70% in some human populations, and folate deficiency in a pregnan...

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Detalhes bibliográficos
Publicado no:Biochimie
Main Authors: Steele, John W, Kim, Sung-Eun, Finnell, Richard H
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253344/
https://ncbi.nlm.nih.gov/pubmed/32061804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2020.02.005
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