Early Fear Memory Defects Are Associated with Altered Synaptic Plasticity and Molecular Architecture in the TgCRND8 Alzheimer's Disease Mouse Model

Alzheimer's disease (AD) is a complex and slowly progressing dementing disorder that results in neuronal and synaptic loss, deposition in brain of aberrantly folded proteins, and impairment of spatial and episodic memory. Most studies of mouse models of AD have employed analyses of cognitive st...

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Detalhes bibliográficos
Publicado no:J Comp Neurol
Main Authors: Steele, John W., Brautigam, Hannah, Short, Jennifer A., Sowa, Allison, Shi, Mengxi, Yadav, Aniruddha, Weaver, Christina M., Westaway, David, Fraser, Paul E., St George-Hyslop, Peter H., Gandy, Sam, Hof, Patrick R., Dickstein, Dara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251468/
https://ncbi.nlm.nih.gov/pubmed/24415002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23536
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