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Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease

Attention deficits in Alzheimer's disease can exacerbate its other cognitive symptoms, yet relevant disruptions of key prefrontal circuitry are not well understood. Here, in the TgCRND8 mouse model of this neurological disorder, we demonstrate and characterize a disruption of cholinergic excita...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Proulx, Éliane, Fraser, Paul, McLaurin, JoAnne, Lambe, Evelyn K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640899/
https://ncbi.nlm.nih.gov/pubmed/26377466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4501-14.2015
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