Association among Amyloid Plaque, Lipid, and Creatine in Hippocampus of TgCRND8 Mouse Model for Alzheimer Disease

Amyloid peptide (Aβ) aggregation in the brain is a characteristic feature of Alzheimer disease (AD). Previously, we reported the discovery of focally elevated creatine deposits in brain tissue from TgCRND8 mice, which express double mutant (K670N/M671L and V717F) amyloid protein precursor. In this s...

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Detalhes bibliográficos
Main Authors: Kuzyk, Alexandra, Kastyak, Marzena, Agrawal, Veena, Gallant, Meghan, Sivakumar, Gajjeraman, Rak, Margaret, Del Bigio, Marc R., Westaway, David, Julian, Robert, Gough, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951194/
https://ncbi.nlm.nih.gov/pubmed/20682779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142174
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