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Latrepirdine (Dimebon(®)), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model
Alzheimer disease (AD) is a form of neurodegeneration that develops over the course of multiple decades and as a result of the accumulation of the pathogenic amyloid-β (Aβ) peptide, also known as A4. In late-stage AD, failure of autophagic clearance results in neuronal cell bodies that are almost en...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627679/ https://ncbi.nlm.nih.gov/pubmed/23380933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23487 |
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