Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation

von Soisson, Stephen M., Parthasarathy, Gopalakrishnan, Adams, Alan D., Sahoo, Soumya, Sitlani, Ayesha, Sparrow, Carl, Cui, Jisong, Becker, Joseph W.
Veröffentlicht 2008

Structural definition and substrate specificity of the S28 protease family: the crystal structure of human prolylcarboxypeptidase

von Soisson, Stephen M, Patel, Sangita B, Abeywickrema, Pravien D, Byrne, Noel J, Diehl, Ronald E, Hall, Dawn L, Ford, Rachael E, Reid, John C, Rickert, Keith W, Shipman, Jennifer M, Sharma, Sujata, Lumb, Kevin J
Veröffentlicht 2010

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

von Clayton, Gina M., Klein, Daniel J., Rickert, Keith W., Patel, Sangita B., Kornienko, Maria, Zugay-Murphy, Joan, Reid, John C., Tummala, Srivanya, Sharma, Sujata, Singh, Sheo B., Miesel, Lynn, Lumb, Kevin J., Soisson, Stephen M.
Veröffentlicht 2013

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

von Michaelian, Nairie, Sadybekov, Anastasiia, Besserer-Offroy, Élie, Han, Gye Won, Krishnamurthy, Harini, Zamlynny, Beata A., Fradera, Xavier, Siliphaivanh, Phieng, Presland, Jeremy, Spencer, Kerrie B., Soisson, Stephen M., Popov, Petr, Sarret, Philippe, Katritch, Vsevolod, Cherezov, Vadim
Veröffentlicht in Nat Commun (2021)

Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase

von Hayes, Robert P., Heo, Mee Ra, Mason, Mark, Reid, John, Burlein, Christine, Armacost, Kira A., Tellers, David M., Raheem, Izzat, Shaw, Anthony W., Murray, Edward, McKenna, Philip M., Abeywickrema, Pravien, Sharma, Sujata, Soisson, Stephen M., Klein, Daniel
Veröffentlicht in Nat Commun (2021)

Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4

von Allen, Samantha J., Parthasarathy, Gopal, Darke, Paul L., Diehl, Ronald E., Ford, Rachael E., Hall, Dawn L., Johnson, Scott A., Reid, John C., Rickert, Keith W., Shipman, Jennifer M., Soisson, Stephen M., Zuck, Paul, Munshi, Sanjeev K., Lumb, Kevin J.
Veröffentlicht in J Biol Chem (2015)

Expression, purification and crystallization of human prolylcarboxypeptidase

von Abeywickrema, Pravien D., Patel, Sangita B., Byrne, Noel J., Diehl, Ronald E., Hall, Dawn L., Ford, Rachael E., Rickert, Keith W., Reid, John C., Shipman, Jennifer M., Geissler, Wayne M., Pryor, Kelly D., SinhaRoy, Ranabir, Soisson, Stephen M., Lumb, Kevin J., Sharma, Sujata
Veröffentlicht 2010

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

von Rickert, Keith W., Patel, Sangita B., Allison, Timothy J., Byrne, Noel J., Darke, Paul L., Ford, Rachael E., Guerin, David J., Hall, Dawn L., Kornienko, Maria, Lu, Jun, Munshi, Sanjeev K., Reid, John C., Shipman, Jennifer M., Stanton, Elizabeth F., Wilson, Kevin J., Young, Jonathon R., Soisson, Stephen M., Lumb, Kevin J.
Veröffentlicht 2011

Identification of an allosteric binding site for RORγt inhibition

von Scheepstra, Marcel, Leysen, Seppe, van Almen, Geert C., Miller, J. Richard, Piesvaux, Jennifer, Kutilek, Victoria, van Eenennaam, Hans, Zhang, Hongjun, Barr, Kenneth, Nagpal, Sunil, Soisson, Stephen M., Kornienko, Maria, Wiley, Kristen, Elsen, Nathaniel, Sharma, Sujata, Correll, Craig C., Trotter, B. Wesley, van der Stelt, Mario, Oubrie, Arthur, Ottmann, Christian, Parthasarathy, Gopal, Brunsveld, Luc
Veröffentlicht in Nat Commun (2015)

A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein

von Tang, Aimin, Chen, Zhifeng, Cox, Kara S., Su, Hua-Poo, Callahan, Cheryl, Fridman, Arthur, Zhang, Lan, Patel, Sangita B., Cejas, Pedro J., Swoyer, Ryan, Touch, Sinoeun, Citron, Michael P., Govindarajan, Dhanasekaran, Luo, Bin, Eddins, Michael, Reid, John C., Soisson, Stephen M., Galli, Jennifer, Wang, Dai, Wen, Zhiyun, Heidecker, Gwendolyn J., Casimiro, Danilo R., DiStefano, Daniel J., Vora, Kalpit A.
Veröffentlicht in Nat Commun (2019)

Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation

von Hong, Chuan, Byrne, Noel J., Zamlynny, Beata, Tummala, Srivanya, Xiao, Li, Shipman, Jennifer M., Partridge, Andrea T., Minnick, Christina, Breslin, Michael J., Rudd, Michael T., Stachel, Shawn J., Rada, Vanessa L., Kern, Jeffrey C., Armacost, Kira A., Hollingsworth, Scott A., O’Brien, Julie A., Hall, Dawn L., McDonald, Terrence P., Strickland, Corey, Brooun, Alexei, Soisson, Stephen M., Hollenstein, Kaspar
Veröffentlicht in Nat Commun (2021)

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

von Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim
Veröffentlicht in Nature (2017)

Structural characterization of nonactive site, TrkA-selective kinase inhibitors

von Su, Hua-Poo, Rickert, Keith, Burlein, Christine, Narayan, Kartik, Bukhtiyarova, Marina, Hurzy, Danielle M., Stump, Craig A., Zhang, Xufang, Reid, John, Krasowska-Zoladek, Alicja, Tummala, Srivanya, Shipman, Jennifer M., Kornienko, Maria, Lemaire, Peter A., Krosky, Daniel, Heller, Amanda, Achab, Abdelghani, Chamberlin, Chad, Saradjian, Peter, Sauvagnat, Berengere, Yang, Xianshu, Ziebell, Michael R., Nickbarg, Elliott, Sanders, John M., Bilodeau, Mark T., Carroll, Steven S., Lumb, Kevin J., Soisson, Stephen M., Henze, Darrell A., Cooke, Andrew J.
Veröffentlicht in Proc Natl Acad Sci U S A (2017)