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Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

Angiotensin II receptors, AT(1)R and AT(2)R, serve as key components of the renin-angiotensin-aldosterone system. While AT(1)R plays a central role in the regulation of blood pressure, the function of AT(2)R is enigmatic with a variety of reported effects. To elucidate the mechanisms for the functio...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525545/
https://ncbi.nlm.nih.gov/pubmed/28379944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22035
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