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An Intellectual Disability-Related Missense Mutation in Rac1 Prevents LTP Induction

The small GTPase Rac1 promotes actin polymerization and plays a critical and increasingly appreciated role in the development and plasticity of glutamatergic synapses. Growing evidence suggests that disruption of the Rac1 signaling pathway at glutamatergic synapses contributes to Autism Spectrum Dis...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Tian, Chen, Kay, Yuni, Sadybekov, Anastasiia, Rao, Sadhna, Katritch, Vsevolod, Herring, Bruce E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049044/
https://ncbi.nlm.nih.gov/pubmed/30042656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00223
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