Biochemical Basis for the Functional Switch That Regulates Hepatocyte Growth Factor Receptor Tyrosine Kinase Activation

Por Sheth, Payal R., Hays, John L., Elferink, Lisa A., Watowich, Stanley J.
Publicado em 2008

Broad Coverage of Genetically Diverse Strains of Clostridium difficile by Actoxumab and Bezlotoxumab Predicted by In Vitro Neutralization and Epitope Modeling

Por Hernandez, Lorraine D., Racine, Fred, Xiao, Li, DiNunzio, Edward, Hairston, Nichelle, Sheth, Payal R., Murgolo, Nicholas J., Therien, Alex G.
Publicado no Antimicrob Agents Chemother (2015)

AFFINITY SELECTION-MASS SPECTROMETRY IDENTIFIES A NOVEL ANTIBACTERIAL RNA POLYMERASE INHIBITOR

Por Walker, Scott S., Degen, David, Nickbarg, Elliott, Carr, Donna, Soriano, Aileen, Mandal, Mihir, Painter, Ronald E., Sheth, Payal, Xiao, Li, Sher, Xinwei, Murgolo, Nicholas, Su, Jing, Olsen, David B., Ebright, Richard H., Young, Katherine
Publicado no ACS Chem Biol (2017)

Mechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography

Por Orth, Peter, Xiao, Li, Hernandez, Lorraine D., Reichert, Paul, Sheth, Payal R., Beaumont, Maribel, Yang, Xiaoyu, Murgolo, Nicholas, Ermakov, Grigori, DiNunzio, Edward, Racine, Fred, Karczewski, Jerzy, Secore, Susan, Ingram, Richard N., Mayhood, Todd, Strickland, Corey, Therien, Alex G.
Publicado em 2014

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

Por Walker, Scott S., Labroli, Marc, Painter, Ronald E., Wiltsie, Judyann, Sherborne, Brad, Murgolo, Nicholas, Sher, Xinwei, Mann, Paul, Zuck, Paul, Garlisi, Charles G., Su, Jing, Kargman, Stacia, Xiao, Li, Scapin, Giovanna, Salowe, Scott, Devito, Kristine, Sheth, Payal, Buist, Nichole, Tan, Christopher M., Black, Todd A., Roemer, Terry
Publicado no PLoS One (2017)

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

Por Mann, Paul A., Müller, Anna, Wolff, Kerstin A., Fischmann, Thierry, Wang, Hao, Reed, Patricia, Hou, Yan, Li, Wenjin, Müller, Christa E., Xiao, Jianying, Murgolo, Nicholas, Sher, Xinwei, Mayhood, Todd, Sheth, Payal R., Mirza, Asra, Labroli, Marc, Xiao, Li, McCoy, Mark, Gill, Charles J., Pinho, Mariana G., Schneider, Tanja, Roemer, Terry
Publicado no PLoS Pathog (2016)

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

Por Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim
Publicado no Nature (2017)