AFFINITY SELECTION-MASS SPECTROMETRY IDENTIFIES A NOVEL ANTIBACTERIAL RNA POLYMERASE INHIBITOR

The growing prevalence of drug resistant bacteria is a significant global threat to human health. The antibacterial drug rifampin, which functions by inhibiting bacterial RNA polymerase (RNAP), is an important part of the antibacterial armamentarium. Here, in order to identify novel inhibitors of ba...

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Publicado no:ACS Chem Biol
Main Authors: Walker, Scott S., Degen, David, Nickbarg, Elliott, Carr, Donna, Soriano, Aileen, Mandal, Mihir, Painter, Ronald E., Sheth, Payal, Xiao, Li, Sher, Xinwei, Murgolo, Nicholas, Su, Jing, Olsen, David B., Ebright, Richard H., Young, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800494/
https://ncbi.nlm.nih.gov/pubmed/28323406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01133
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