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Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry
Determination of the impact of individual antibody glycoforms on FcɣRIIIa affinity, and consequently antibody-dependent cell-mediated cytotoxicity (ADCC) previously required high purity glycoengineering. We hyphenated FcɣRIIIa affinity chromatography to mass spectrometry, which allowed direct affini...
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| Udgivet i: | MAbs |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748599/ https://ncbi.nlm.nih.gov/pubmed/31276431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1636602 |
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