Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry

Determination of the impact of individual antibody glycoforms on FcɣRIIIa affinity, and consequently antibody-dependent cell-mediated cytotoxicity (ADCC) previously required high purity glycoengineering. We hyphenated FcɣRIIIa affinity chromatography to mass spectrometry, which allowed direct affini...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Lippold, Steffen, Nicolardi, Simone, Domínguez-Vega, Elena, Heidenreich, Anna-Katharina, Vidarsson, Gestur, Reusch, Dietmar, Haberger, Markus, Wuhrer, Manfred, Falck, David
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748599/
https://ncbi.nlm.nih.gov/pubmed/31276431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1636602
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