Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry

Determination of the impact of individual antibody glycoforms on FcɣRIIIa affinity, and consequently antibody-dependent cell-mediated cytotoxicity (ADCC) previously required high purity glycoengineering. We hyphenated FcɣRIIIa affinity chromatography to mass spectrometry, which allowed direct affini...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Lippold, Steffen, Nicolardi, Simone, Domínguez-Vega, Elena, Heidenreich, Anna-Katharina, Vidarsson, Gestur, Reusch, Dietmar, Haberger, Markus, Wuhrer, Manfred, Falck, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
Onderwerpen:
Short Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748599/
https://ncbi.nlm.nih.gov/pubmed/31276431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1636602
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