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Affinity purification of erythropoietin from cell culture supernatant combined with MALDI-TOF-MS analysis of erythropoietin N-glycosylation

Erythropoietin (EPO) is a heavily glycosylated hormone whose recombinant forms are used for treatment of anaemia. EPO glycosylation is important for its pharmacological properties. An analytical workflow, which can determine EPO glycosylation in an accurate and high-throughput fashion from cell cult...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Falck, David, Haberger, Markus, Plomp, Rosina, Hook, Michaela, Bulau, Patrick, Wuhrer, Manfred, Reusch, Dietmar
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509673/
https://ncbi.nlm.nih.gov/pubmed/28706253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05641-1
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