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Affinity purification of erythropoietin from cell culture supernatant combined with MALDI-TOF-MS analysis of erythropoietin N-glycosylation

Erythropoietin (EPO) is a heavily glycosylated hormone whose recombinant forms are used for treatment of anaemia. EPO glycosylation is important for its pharmacological properties. An analytical workflow, which can determine EPO glycosylation in an accurate and high-throughput fashion from cell cult...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Falck, David, Haberger, Markus, Plomp, Rosina, Hook, Michaela, Bulau, Patrick, Wuhrer, Manfred, Reusch, Dietmar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509673/
https://ncbi.nlm.nih.gov/pubmed/28706253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05641-1
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