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High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer

The Fc glycosylation of therapeutic antibodies is crucial for their effector functions and their behavior in pharmacokinetics and pharmacodynamics. To monitor the Fc glycosylation in bioprocess development and characterization, high-throughput techniques for glycosylation analysis are needed. Here,...

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Main Authors: Reusch, Dietmar, Haberger, Markus, Kailich, Tobias, Heidenreich, Anna-Katharina, Kampe, Michael, Bulau, Patrick, Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929442/
https://ncbi.nlm.nih.gov/pubmed/24135630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26712
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