Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods

Immunoglobulin G (IgG) crystallizable fragment (Fc) glycosylation is crucial for antibody effector functions, such as antibody-dependent cell-mediated cytotoxicity, and for their pharmacokinetic and pharmacodynamics behavior. To monitor the Fc-glycosylation in bioprocess development, as well as prod...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Reusch, Dietmar, Haberger, Markus, Maier, Bernd, Maier, Maria, Kloseck, Ronny, Zimmermann, Boris, Hook, Michaela, Szabo, Zoltan, Tep, Samnang, Wegstein, Jo, Alt, Nadja, Bulau, Patrick, Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623496/
https://ncbi.nlm.nih.gov/pubmed/25524468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.986000
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